This trophy is called "Did You Think I'd Let You Get Away?" and it requires you to destroy a section as the Raider which contains two survivors when it explodes.
This is really luck based unfortunately and there aren't any key tips I can provide which would guarantee the trophy.
While playing as the Raider, when you reach a new level, you'll have the ability to destroy a section with L1 + R1. When you press them, use the Right Stick to look around at the sections then press the Square Button to confirm which section to destroy.
While you're up in the sky, you can see little black ant looking specs moving around at certain distances. Those are the Survivors. That's one way to help determine where to go.
Something to try is to down a Survivor deep into an area and fly out in hopes that it will lure others in for the revive. Just wait several seconds after leaving and then destroy the city. A note, but not a tip, is that users with the Emergency Escape Device will count as being "downed" even though they aren't.
Other than that, destroy sections where the power key have been obtained, but not set. Same thought process as downed Survivors. Hoping the unset key will lure people to the area to set it and you can hopefully catch them in the blast.