I did this by accident, but the point I did it is after the Point-of-no-return.
The iconoclasts (if you sided with then instead of MSI) will blast their way in with chemical weapons and energy weapons.
Hit some one with the n-ray damage. give your companions weapon damage that compliments yours, having three types of damage. I did this by allowing the Iconoclasts to take point and hitting them from a distance. If you struggle, Nyoka's avility does a form of elemental damage and can be used to make up the fifth if you have to.