To earn the "RUN KARA RUN" trophy in Detroit: Become Human, you must evade police during the "ON THE RUN" chapter.
If you start in the Motel, run a bath for Alice and cut and colour your hair at the mirror. Check the TV news. Head outside to get food. You'll switch to Connor - in my play-through I ended up annoying Hank, it's unclear at the moment whether that impacts the rest of the scene. Hank busts into the room but Kara is gone.
Back in control of Kara, you must avoid the police as you head towards the train station. This is relatively straight-forward, just make sure to keep holding
to survey what's around you. You'll have to hide from one set of cops immediately ahead and then cross the road, quickly turning right to avoid the cop on the opposite side of the street. Hide at the bus shelter next, and then cross the street before the next cop sees you. Grab the umbrella and hold it up as more cops pass, and then approach the ATM on the right as a cop appears from out of an alleyway. That should get you to the station where the scene ends. You'll get your trophy during the flowchart.
SolaceCreed adds: If Kara is caught during the escape, your control will switch to Connor. If you stand still for a minute as Connor before running a short distance this will allow Kara enough time to escape from the police. Thanks SolaceCreed!