This trophy is technically story related, but I suppose if you wanted to try and avoid it, it isn't mandatory. Unlocked with hideouts, you will find that there are workbenches that you can make cure tonics, disassemble junk you find along the way, and even upgrade your weaponry. This trophy will unlock as you upgrade a weapon, which will probably be one of the first two weapons you come across (the machete, revolver, or stake). Simply upgrade it to the proceeding level to get this trophy.