Come well prepared with ammo. Even on the easiest difficulty, Marguerite takes a lot of damage. After meeting Marguerite in the "Old House", get past the spider blocked door and instead of trying to avoid her, attack her. Use everything you have against her, eventually she will throw you to the ground and leave the area (she will no longer be patrolling the "Old House").
Here is a video guide with English commentary!
Here is a playlist of guides for this game!
https://www.youtube.com/playlist?list=PL-HeW6XkKdUKUtj7CV_kW...