I believe the first chance to get this trophy is in the Medical Pavilion foyer. On the south side of the foyer is Twilight Fields Funeral Homes. The door is iced over so you will need the Incinerator plasmid from Eternal Flame Crematorium before you can access this area. When you get the plasmid, melt the ice covering the door and walk in. On the left is a little area with a splicer hiding behind the desk. Take care of the splicer and walk behind the desk where it was standing. There will be a couple of things on the ground (alcohol, money, ammo, etc.). I believe picking either the money or the ammo up is what triggers the turret. So pick up the items (I didn’t pick up the alcohol) and look up at the other end of the room and you will notice now a wall has opened up (maybe was a curtain, honestly can’t remember) and there will be a turret sitting in front of a safe. Either destroy or hack the turret and you will get access to get to the safe. Now the hacking for the safes is much harder than the other things but still doable if you are quick. You can either play the mini-game or buyout for a much more expensive $91 (I think the buyout just depends on the quality of the stuff in the safe) if you have the funds. Or you can just go to the room opposite this one on the other side of reception, take care of the splicer in there, hack the door (code is 0451) and there is an Autohack tool that you can use on the safe, saving yourself time, frustration and money. Once it is hacked, the trophy will pop.