There's a number of ways to make this less risky.
1. Do it on your file with extra weapons unlocked (unlimited magnum, rocket launcher, submachine gun) provided it's not hard mode. If your file is hard mode there's still a good chance a monkey could stun lock you and you'll be finished.
2. Start an easy game file. You have to actually go out of your way to die in easy mode and there's no instant kill enemy so this should make it much easier.
3. Do a Wesker Mode run. Wesker is incredibly overpowered and should make this a cinch. Even better if you have extra weapons unlocked.
I wouldn't recommend trying this on your first run as the game can throw some surprises at you that you'll be able to handle better with knowledge on the game first.