The I Shot The Meriff trophy in Borderlands: The Pre-Sequel is story-related and can't be missed.
You will unlock the trophy after completing the game's fifth story mission "A New Direction".
*** Spoiler - click to reveal ***- Reach Crisis Scar
-Pick up prisms: 0/3
- Kill Darksiders: 0/20
- Report to SC4V-TP
- Go to secret entrance
- Use intercom at secret entrance
- Reach Crisis Scar unnoticed
- Find signal source
- Defeat gate guards
- Find signal source
- Kill RedBelly
- Turn off signal
- Use maintenance console
- Destroy relays 0/3
- Return to Concordia
- Meet Jack in Concordia
- Find CU5TM-TP
- Follow CU5TM-TP
- Confront the Meriff
- Get to Springs