It's best if you don't worry about this too much until the end of the game. Getting the Drone Teleport and Red Coat allow you access to the entire map, as well as making some difficult sections far easier to get through. You'll need to collect 20 weapons in all, not counting anything you might find in a Secret World. While this can be collected on its own, you will need to do this on the way to finishing the 100% Items trophy.
The 100% Items trophy in Axiom Verge worth 227 pointsAcquire 100% of all weapons, tools, upgrades, and notes. Axiom Disruptor
Nova
Kilver
Firewall
Hypo-Atomizer
Reflector
Orbital Discharge
Shards
Distortion Field
Quantum Variegator
Ion Beam
Tethered Charge
Flamethrower
Multi-Disruptor
Lightning Gun
Data bomb
Intertial Pulse
Voranj
Turbine Pulse
Reverse Slicer
If you hit a dead end where there should be more room, try to teleport through what look like solid walls. If that doesn't work, remember that passwords can open up new sections.
Passwords- In Eribu, there will be a hallway leading left and through a checkpoint. Go through here to the next hallway and break through the drill wall in the upper left next to the ceiling. Follow the path to the left as far as you can and you'll eventually find a weapon upgrade behind a thick wall. Use "DINGER-GISBAR" to make the wall thinner.
- In Eribu, in the bottom most 2x2 room, go to the upper left corner of the room (you'll see some weird letters written in the rock above you) and enter "DALKHU-SUBTUM" to open a new path.
- In E-Kur-Mah, you'll enter a large 6x3 vertical room. Enter "ISKART-EHANZU" to open a new path to a blocked off section in the middle of the left side of the room. You'll have to enter this section from the bottom.