My strategy was to focus on shooting Ukhu's mouth with the Inertial Pulse as its shots capable of traveling through his tail to do damage. The Inertial Pulse is found in a medium-sized room across from the furthest right save room in Absu, above the lower right exit. The Address Disruptor 2 is needed to pass a glitched barrier inside this room.
When the wasps were released I switched to the Lightning Gun as it requires very little aiming on your part and locks on to them, destroying them quickly before they can reach you. The Lightning Gun is located in the lower-mid section of Eribu, past some Level 3 corruption in the upper-left section of a vertical shaft.
Using this method, the fight was over in half a minute.