| Name | Description |
| Persistence Pays Dividends | Collect all trophies |
| Let's Do This | Enter Research Deck after the tutorial |
| Plot the Jump Vectors | Plot the jump vectors home on Research Deck |
| Mutant Madness | Refuel the Stardrive |
| Repair the Sensors | Repair the Sensors on Communications Deck |
| A Fallen Hero | Find the Captain's body on Engineering Deck |
| Going Home! | Complete the game |
| Hidden Trophy | Continue playing to unlock this trophy. |
| Treasure Hunter | Open 25 supply crates |
| First of Many | Make any schematic |
| Epic! | Make an epic schematic |
| Everything is Awesome! | Make an Epic of each suit, teleporter, shield, harvester and supersense |
| Payback Time | Unlock a weapon |
| Full Arsenal | Unlock all weapons |
| Lock and Load | Upgrade a weapon |
| As Good as it Gets | Get any weapon to Max level |
| Feeling Good | Upgrade any DNA stat |
| Feeling Great | Upgrade each DNA stat at least once |
| Feeling Unstoppable | Get all DNA stats to max |
| Samurai | Kill 100 enemies by harvesting their stemcells |
| Six Shooter | Shoot and kill 6 enemies in a row, with just 6 bullets |
| Sharp Shooter | 10 headshots in a row |
| A Bundle of Limbs | Kill 3 enemies with the same gravity bomb |
| Thanks, Guys! | Kill 5 enemies with the same Swarm Droid |
| That's Gotta Hurt | Smash an enemy to death with the Gravimetric Hook |
| Abrakebabra! | Pin two enemies with the same Valkyrie bolt |
| Stealth is for Wimps | Melee kill a Berserker with the Stem Cell Harvester |
| Who's a Good Boy! | Have a single Ivy Serum buddy kill 5 enemies |
| Shields Up! | Power up any Debris Defence Shield machine |
| Shields at Maximum | Power up all the Debris Defence Shield machines |
| Fully Fortified | Use all 4 Debris Defence Shield machines on the same life |
| A Lost Friend | Find a crew member artefact |
| A Lost Family | Find all 6 crew member artefacts |
| Not Feeling Myself… | Print a clone of any other crew member |
| All the Crew | Print a clone of all 7 crew members |
| Full House | Kill one of each type of enemy |
| The Ship is Your Friend | Use the environment to kill 10 enemies |
| Big Bad Buddy | Rage Berserkers to kill 10 enemies |
| Thank You! | Get a weeper to kill another mutant (without using Ivy Serum) |
| Wrong Place, Wrong Time | Kill any enemy with a hidden Siren Grenade |
| Keep Your Distance, Buddy | Use your shield 10 times against the same enemy |
| Boom! | Get fireballs to kill a total of 10 mutants |
| Teleport Technician | Visit Research and then Stardrive decks on any one life, without walking |
| Nah, I'm Good. | Visit all 4 Decks on any 1 life, without collecting anything or making a weapon |