Most of the trophies don't require a set difficulty, so all can be done on the Amateur difficulty if it isn't stated otherwise. On top of that, you can adjust some sliders to correct the difficulty level of your own players or those from the AI-opponents. Note that these settings don't apply when playing Games of The Week or Ultimate Team. Obviously these settings won't apply to online opponents either.
There are no Virtual Pro game-modes included on the Xbox 360 or PS3 versions. A bit of a surprise, but nothing to worry about as you can unlock all trophies just fine while playing other game-modes.
Note: The EXP you should receive after playing Games of The Week doesn't get awarded, so it's impossible to boost your level with these. Win cups online or in single player seasons to gain the most.
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