- Showtime!
Complete the game on Devil Hunter mode as Nero, Dante, or V .
- Doing Daddy Proud
Complete the game on Son of Sparda mode as Nero, Dante, or V.
- Dance with the Devil
Complete the game on Dante Must Die mode as Nero, Dante, or V.
- Stairway to Heaven
Complete the game on Heaven or Hell mode as Nero, Dante, or V.
- Highway to Hell
Complete the game on Hell and Hell mode as Nero, Dante, or V.
- Fall from Grace
Clear the Prologue Mission as Nero, Dante, or V.
- Protect the People
Defeat all enemies in Mission 01 as Nero, Dante, or V.
- Where the Red Orbs Grow
Collect Red Orbs from an unexpected spot in Mission 02 as Nero, Dante, or V.
- Reunion
Clear Mission 03 as Nero, Dante, or V.
- Backroad
Destroy a certain wall in Mission 04 as Nero, Dante, or V.
- Break a Leg
Fend off a menace from above in Mission 05 as Nero, Dante, or V.
- End of the Line
Clear Mission 06 as Nero, Dante, or V.
- Share the Pain
Clear Mission 07 with both Nero and V.
- Light in the Darkness
Clear Mission 08 as Nero, Dante, or V.
- Eagle-Eyed
Destroy a certain wall in Mission 09 as Nero, Dante, or V.
- This Ain't Over
Clear Mission 10 as Nero, Dante, or V.
- Don't Mess with the Best
Use proper timing to get a leg up in battle against the boss in Mission 11 as Nero, Dante, or V.
- The Qliphoth
Clear Mission 12 as Nero, Dante, or V.
- Each In His Own Way
Clear Mission 13 as Nero, Dante, and V.
- Gotta Hurry
Clear Mission 14 as Nero, Dante, or V.
- Slick Moves
Proceed with caution and avoid unneeded damage in Mission 15 as Nero, Dante, or V.
- Obedience Training
Go on the offensive in a roundabout way in the Mission 16 boss battle as Nero, Dante, or V.
- Back to Life
Clear Mission 17 as Nero, Dante, or V.
- Man on a Mission
Clear Mission 18 as Nero, Dante, or V.
- Battle for the Ages
Clear Missions 19 and 20 without continuing as Nero, Dante, or V. (Heaven or Hell excluded)
- Not Too Shabby
Perform a Stylish Rank S combo.
- Steppin' up the Style
Perform a Stylish Rank SS combo.
- Seriously Stylish Slaying!
Perform a Stylish Rank SSS combo.
- Secrets Exposed
Clear all secret missions as Nero, Dante, or V.
- The Quick and the Dead
Defeat 5 enemies in 1 second.
- Well I'll Be Damned
Wield overwhelming power to exact an unexpected conclusion as Dante, Nero, or V.
- Hell of a Hunter
Clear all missions with S rank as Nero, Dante, or V.
- Worthy of Legend
Clear all missions with S rank on all difficulties as Nero, Dante, or V. (HoH, LDK excluded)
- I Believe I Can Fly
Rack up a total of 60 minutes in the air by jumping or other means
- Nothing's Impossible
Acquire all of Nero's skills.
- Be the Legend
Acquire all of Dante's skills.
- Demon Breeder
Acquire all of V's skills.
- Physical Perfection
Upgrade your vitality gauge to max.
- The Devil's Own
Upgrade your Devil Trigger Gauge to max.
- A New Job
Accept a new job from Morrison after the Red Grave incident. (Dante only)
- Jackpot!
Collect more than 1,000,000 Red Orbs total.
- Demon Destroyer
Defeat 1,000 enemies total.
- Rearm and Repeat
Collect more than 100 Devil Breakers during missions. (Nero only)
- Dante the Gambler
Use more than 500,000 Red Orbs total with Dr. Faust.
- Who Needs Weapons Anyway?
Clear Mission 11 without equipping a weapon set for Dante. (Heaven or Hell excluded)
- Unarmed and Dangerous
Beat Mission 07 without any starting Devil Breakers equipped. (Heaven or Hell excluded)
- Pet Protection
Clear Mission 05 without V's demons getting stalemated. (Heaven or Hell excluded)
- Sibling Rivalry
Clear all missions as Vergil.
- Concentrated Strength
Acquire all of Vergil's skills.
- Heart of a Swordsman
Clear Mission 19 as Vergil without using any weapons other than Yamato. (Heaven or Hell excluded)
- A Legendary Return
Complete the game on Legendary Dark Knight mode.
- A Champion Rises
Clear the Bloody Palace with any character.
- Four Infernal Kings
Clear the Bloody Palace with all characters.